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7-hydroxyamoxapine

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EntityQ4642870· pop 6· linked from 3 articles

7-hydroxyamoxapine

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7-Hydroxyamoxapine is an active metabolite of the antidepressant drug amoxapine (Asendin). It contributes to amoxapine's pharmacology. It is a dopamine receptor antagonist and contributes to amoxapine's antipsychotic properties.

Chemical data

Formula
C17H16ClN3O2
Molecular weight
329.8 g/mol
IUPAC name
8-chloro-6-piperazin-1-ylbenzo[b][1,4]benzoxazepin-2-ol
SMILES
C1CN(CCN1)C2=NC3=C(C=C(C=C3)O)OC4=C2C=C(C=C4)Cl
InChIKey
MEUGUMOVYNSGEW-UHFFFAOYSA-N
XLogP
2.2
Polar surface area
57.1 Ų
H-bond donors
2
H-bond acceptors
4
Formal charge
0

via PubChem

Wikidata facts

Mass
329.093
Show 2 more facts
chemical formula
C₁₇H₁₆ClN₃O₂
canonical SMILES
C1CN(CCN1)C2=NC3=C(C=C(C=C3)O)OC4=C2C=C(C=C4)Cl
Sources (2)

via Wikidata · CC0

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Encyclopedic overview

2 sections
Contents
  • See also
  • References

7-Hydroxyamoxapine is an active metabolite of the antidepressant drug amoxapine (Asendin). It contributes to amoxapine's pharmacology. It is a dopamine receptor antagonist and contributes to amoxapine's antipsychotic properties.

== See also == 8-Hydroxyamoxapine

Excerpted from Wikipedia’s “7-hydroxyamoxapine” article, available under the CC BY-SA 4.0 licence.

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