ACOT13
Sign in to saveAlso known as PNAS-27, THEM2, HT012, acyl-CoA thioesterase 13
Acyl-CoA thioesterase 13 is a protein that in humans is encoded by the ACOT13 gene. This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation.
Gene data
ACOT13- Name
- acyl-CoA thioesterase 13
- Type
- protein-coding
- Position
- 24,666,901–24,714,084 (+)
- Aliases
- HT012, PNAS-27, THEM2
- Ensembl
- ENSG00000112304
- RefSeq RNA
- NM_001160094.2, NM_018473.4
- RefSeq protein
- NP_001153566.1, NP_060943.1
This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation. The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2009].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
acyl-CoA thioesterase 13
- Symbol
- ACOT13
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:24,666,901-24,714,084
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 41273
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/55856
- genomic end
- 24705293
- genomic start
- 24667263
- chromosome
- human chromosome 6
- cytogenetic location
- 6p22.3
Sources (4)
via Wikidata · CC0
~3 min read
Encyclopedic overview
5 sectionsContents
- Structure
- Function
- References
- External links
- Further reading
Acyl-CoA thioesterase 13 is a protein that in humans is encoded by the ACOT13 gene. This gene encodes a member of the thioesterase superfamily. In humans, the protein co-localizes with microtubules and is essential for sustained cell proliferation.
== Structure == The orthologous mouse protein forms a homotetramer and is associated with mitochondria. The mouse protein functions as a medium- and long-chain acyl-CoA thioesterase. Multiple transcript variants encoding different isoforms have been found for this gene.
Excerpted from Wikipedia’s “ACOT13” article, available under the CC BY-SA 4.0 licence.