UCHL1

Also known as HEL-117, NDGOA, PARK5, PGP 9.5, PGP9.5, PGP95, Uch-L1, HEL-S-53

protein-coding gene in the species Homo sapiens

Gene data

UCHL1

Name: ubiquitin C-terminal hydrolase L1
Type: protein-coding
Position: 41,256,413–41,268,560 (+)
Aliases: HEL-117, HEL-S-53, NDGOA, PARK5, PGP 9.5, PGP9.5, PGP95, SPG79, SPG79A, UCHL-1
Ensembl: ENSG00000154277
RefSeq RNA: NM_004181.5
RefSeq protein: NP_004172.2

The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009].