AIF1
Sign in to saveAlso known as AIF-1, IBA1, IRT-1, IRT1, allograft inflammatory factor 1, Iba-1
protein-coding gene in the species Homo sapiens
Gene data
AIF1- Name
- allograft inflammatory factor 1
- Type
- protein-coding
- Position
- 31,615,214–31,617,025 (+)
- Aliases
- AIF-1, IBA1, IRT-1, IRT1
- Ensembl
- ENSG00000204472
- RefSeq RNA
- NM_001318970.2, NM_001623.5, NM_004847.3, NM_032955.3, XM_005248870.5
- RefSeq protein
- NP_001305899.1, NP_001614.3, NP_116573.1, XP_005248927.1, XP_054185722.1
This gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full-length and coding nature of some of these variants is not certain. [provided by RefSeq, Jan 2016].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Gene · Ensembl
allograft inflammatory factor 1
- Symbol
- AIF1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HSCHR6_MHC_QBL_CTG1:2,871,006-2,872,843
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI