EF-hand-containing proteins

thumb|The helix–loop–helix structure of the calcium-binding EF hand motif Calmodulin (CaM) (an abbreviation for calcium-modulated protein) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the binding of Ca2+ is required for the activation of calmodulin. Once bound to Ca2+, calmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins such as kinases or phosphatases.

Fimbrin also known as is plastin 1 is a protein that in humans is encoded by the PLS1 gene. Fimbrin is an actin cross-linking protein important in the formation of filopodia.

Actinin is a microfilament protein. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinates contractions between sarcomeres in the horizontal axis. Alpha-actinin is a part of the spectrin superfamily. This superfamily is made of spectrin, dystrophin, and their homologous and isoforms. In non-muscle cells, it is found by the actin filaments and at the adhesion sites. The lattice like arrangement provides stability to the muscle contractile apparatus. Specifically, it helps bind actin filaments to the cell membrane.

Parvalbumin (PV) is a calcium-binding protein with low molecular weight (typically 9–11 kDa). In humans, it is encoded by the PVALB gene. It is a member of the albumin family; it is named for its size (parv-, from Latin '''' which means "small") and its ability to coagulate.

Alpha-actinin-1 is a protein that in humans is encoded by the ACTN1 gene.

Calcium and integrin-binding protein 1 is a protein that in humans is encoded by the CIB1 gene and is located in chromosome 15. The protein encoded by this gene is a member of the calcium-binding protein family. The specific function of this protein has not yet been determined; however this protein is known to interact with DNA-dependent protein kinase and may play a role in kinase-phosphatase regulation of DNA end-joining. This protein also interacts with integrin alpha(IIb)beta(3), which may implicate this protein as a regulatory molecule for alpha(IIb)beta(3).

family of transport proteins

Calpain-9 is a protein that in humans is encoded by the CAPN9 gene.

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

Kv channel-interacting protein 1 also known as KChIP1 is a protein that in humans is encoded by the KCNIP1 gene.

NADPH oxidase, EF-hand calcium binding domain 5, also known as NOX5, is a protein which in humans is encoded by the NOX5 gene.

protein-coding gene in the species Homo sapiens

Ras guanyl-releasing protein 3 is a protein that in humans is encoded by the RASGRP3 gene.

protein-coding gene in the species Homo sapiens

EF-hand domain-containing protein 1 is a protein that in humans is encoded by the EFHC1 gene.

RAS guanyl-releasing protein 1 is a protein that in humans is encoded by the RASGRP1 gene.

Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the ACTN3 gene (named sprinter gene, speed gene or athlete gene) located on chromosome 11. All people have two copies (alleles) of this gene.

protein-coding gene in the species Homo sapiens

Calmodulin-like protein 5 is a protein that in humans is encoded by the CALML5 gene.

Calumenin is a protein that in humans is encoded by the CALU gene.

Rab11 family-interacting protein 3 is a protein that in humans is encoded by the RAB11FIP3 gene.

Myosin light chain, phosphorylatable, fast skeletal muscle is a protein that in humans is encoded by the MYLPF gene. It is located on chromosome 16 in humans. Myosin light chain, phosphorylatable

RAS guanyl-releasing protein 2 is a protein that in humans is encoded by the RASGRP2 gene.

Plastin-3 is a highly conserved protein that in humans is encoded by the PLS3 gene on the X chromosome.

Diacylglycerol kinase alpha is an enzyme that in humans is encoded by the DGKA gene.

mammalian protein found in Homo sapiens

TBC1 domain family member 9 is a protein that in humans is encoded by the TBC1D9 gene.

Myosin light chain 3, skeletal muscle isoform is a protein that in humans is encoded by the MYL1 gene.

45 kDa calcium-binding protein is a protein that in humans is encoded by the SDF4 gene.

Epidermal growth factor receptor substrate 15-like 1 is a protein that in humans is encoded by the EPS15L1 gene.

protein-coding gene in the species Homo sapiens

Alpha-actinin-2 is a protein which in humans is encoded by the ACTN2 gene. This gene encodes an alpha-actinin isoform that is expressed in both skeletal and cardiac muscles and functions to anchor myofibrillar actin thin filaments and titin to Z-discs.

Calcium-binding atopy-related autoantigen 1 is a protein that in humans is encoded by the CBARA1 gene.

Calmodulin-like protein 3 is a protein that in humans is encoded by the CALML3 gene.

Myosin light chain 6B is a protein that in humans is encoded by the MYL6B gene. Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in both slow-twitch skeletal muscle and in nonmuscle tissue.

protein-coding gene in the species Homo sapiens

Dystonin (DST), also known as bullous pemphigoid antigen 1 (BPAG1), isoforms 1/2/3/4/5/8, is a protein that in humans is encoded by the DST gene.

Myosin regulatory light polypeptide 9 is a protein that in humans is encoded by the MYL9 gene.

Ninein is a protein that in humans is encoded by the NIN gene.

protein-coding gene in the species Homo sapiens

Calcyphosin is a protein that in humans is encoded by the CAPS gene.

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

N-terminal EF-hand calcium-binding protein 2 is a protein that in humans is encoded by the NECAB2 gene.

FK506-binding protein 10 is a protein that in humans is encoded by the FKBP10 gene.

Calcineurin subunit B type 2 is a protein that in humans is encoded by the PPP3R2 gene. Among its related pathways are MAPK signaling pathway and GPCR pathway. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CHP1.

EF-hand domain family member D2 is a protein that in humans is encoded by the EFHD2 gene.

FK506-binding protein 9 is a protein that in humans is encoded by the FKBP9 gene.

Plastin-2 is a protein that in humans is encoded by the LCP1 gene.

protein-coding gene in the species Homo sapiens

Kv channel-interacting protein 4 is a protein that in humans is encoded by the KCNIP4 gene.

protein-coding gene in the species Homo sapiens

Secretagogin is a protein that in humans is encoded by the SCGN gene.