Gene data
AIM2- Name
- absent in melanoma 2
- Type
- protein-coding
- Position
- 159,056,129–159,188,222 (−)
- Aliases
- PYHIN4
- Ensembl
- ENSG00000163568
- RefSeq RNA
- NM_001348247.2, NM_004833.3, XM_047434808.1, XM_047434809.1, XM_047434811.1
- RefSeq protein
- NP_001335176.1, NP_004824.1, XP_047290764.1, XP_047290765.1, XP_047290767.1
AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
activation of innate immune responseactivation of innate immune responseactivation of innate immune responsepattern recognition receptor signaling pathwaypositive regulation of defense response to virus by hostpositive regulation of defense response to virus by hostimmune responseDNA damage response
Molecular function
Cellular component
Pathways
NOD-like receptor signaling pathway - Homo sapiens (human)Cytosolic DNA-sensing pathway - Homo sapiens (human)Innate Immune SystemInnate Immune SystemImmune SystemImmune SystemNucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathwaysNucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathwaysCytosolic sensors of pathogen-associated DNA Inflammasomes
via MyGene.info
Gene · Ensembl
absent in melanoma 2
- Symbol
- AIM2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:159,056,129-159,188,222
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 83226
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9447
- genomic end
- 159187843
- genomic start
- 159061599
- chromosome
- human chromosome 1
- cytogenetic location
- 1q23.1|1q23.1-q23.2
- expressed in
- gonad
via Wikidata · CC0