alcaftadine
Sign in to saveAlcaftadine, sold under the brand name Lastacaft, is an antihistamine used to help prevent itching of the eyes. It is an H1 histamine receptor antagonist. It is given as an drops in the eye.
Key facts
- Drug.Verifiedfields
- changed
- Drug.Watchedfields
- changed
- Drug.verifiedrevid
- 477316420
- Drug.image
- Alcaftadine.svg
- Drug.image_class
- skin-invert-image
- Drug.tradename
- Lastacaft
- Drug.MedlinePlus
- a611022
- Drug.DailyMedID
- Alcaftadine
- Drug.routes_of_administration
- Eye drops
- Drug.ATC_prefix
- S01
- Drug.ATC_suffix
- GX11
- Drug.legal_US
- OTC
- Drug.elimination_half life
- ~2 hrs
- Drug.CAS_number
- 147084-10-4
- Drug.PubChem
- 19371515
- Drug.IUPHAR_ligand
- 7587
- Drug.DrugBank
- DB06766
- Drug.ChemSpiderID
- 14201635
via Wikipedia infobox
Chemical data
- Formula
- C19H21N3O
- Molecular weight
- 307.4 g/mol
- IUPAC name
- 11-(1-methylpiperidin-4-ylidene)-5,6-dihydroimidazo[2,1-b][3]benzazepine-3-carbaldehyde
via PubChem
Research
39 papers- Comparative assessment of alcaftadine and olopatadine for allergic conjunctivitis: a meta-analysis.Postepy dermatologii i alergologii · 2024
- Alcaftadine for the prevention of itching associated with allergic conjunctivitis.The Annals of pharmacotherapy · 2012
- Alcaftadine: a topical antihistamine for use in allergic conjunctivitis.Drugs of today (Barcelona, Spain : 1998) · 2011
- Cutaneous Calcium/Calmodulin-Dependent Protein Kinase II-γ-Positive Sympathetic Nerves Secreting Norepinephrine Dictate Psoriasis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
- Alcaftadine 0.25% versus Olopatadine 0.1% in Preventing Cedar Pollen Allergic Conjunctivitis in Japan: A Randomized Study.Ocular immunology and inflammation · 2019
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- +307.168
Show 2 more facts
- P2868
- H1 antagonist
- P366
- medication
via Wikidata · CC0
Article
9 sectionsContents
- Medical uses
- Pharmacology
- Adverse effects
- Pharmacokinetics
- History
- Society and culture
- Economics
- Legal status
- References
Alcaftadine, sold under the brand name Lastacaft, is an antihistamine used to help prevent itching of the eyes. It is an H1 histamine receptor antagonist. It is given as an drops in the eye.
It was approved for medical use in the United States in July 2010. It is available as a generic medication and as an over-the-counter medication.