Structure via PubChem · Public domain (PubChem)
alphacetylmethadol
Sign in to saveAlphacetylmethadol (INN), or α-acetylmethadol (AAM), is a synthetic opioid analgesic. Its levorotary enantiomer, levacetylmethadol, is an FDA-approved treatment for opioid addiction; however as of 2003 it is no longer used in the United States for this purpose. Alphacetylmethadol is very similar in structure to methadone, a widely prescribed treatment for opioid addiction. In the United States, it is a Schedule I controlled substance under the Controlled Substances Act (presumably because it was never marketed in the US, as is the case with other common opiate/opioid medications such as heroin
Chemical data
- Formula
- C23H31NO2
- Molecular weight
- 353.5 g/mol
- IUPAC name
- [(3R,6R)-6-(dimethylamino)-4,4-diphenylheptan-3-yl] acetate
- SMILES
- CC[C@H](C(C[C@@H](C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)OC(=O)C
- InChIKey
- XBMIVRRWGCYBTQ-XMSQKQJNSA-N
- XLogP
- 4.3
- Polar surface area
- 29.5 Ų
- H-bond donors
- 0
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- methadyl acetate
- Mass
- 353.235479
Show 4 more facts
- chemical formula
- C₂₃H₃₁NO₂
- isomeric SMILES
- CC[C@H](C(C[C@@H](C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)OC(=O)C
- canonical SMILES
- CCC(C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)OC(=O)C
- stereoisomer of
- levomethadyl acetate
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Alphacetylmethadol (INN), or α-acetylmethadol (AAM), is a synthetic opioid analgesic. Its levorotary enantiomer, levacetylmethadol, is an FDA-approved treatment for opioid addiction; however as of 2003 it is no longer used in the United States for this purpose. Alphacetylmethadol is very similar in structure to methadone, a widely prescribed treatment for opioid addiction. In the United States, it is a Schedule I controlled substance under the Controlled Substances Act (presumably because it was never marketed in the US, as is the case with other common opiate/opioid medications such as heroin and prodine), with an ACSCN of 9603 and a 2013 annual manufacturing quota of 2 grammes.
== See also == Levacetylmethadol Acetylmethadol Betacetylmethadol Alphamethadol
Excerpted from Wikipedia’s “alphacetylmethadol” article, available under the CC BY-SA 4.0 licence.