Ameloblastin (abbreviated AMBN and also known as sheathlin or amelin) is an enamel matrix protein that in humans is encoded by the AMBN gene.
Ameloblastin (abbreviated AMBN and also known as sheathlin or amelin) is an enamel matrix protein that in humans is encoded by the AMBN gene.
== Function == Ameloblastin is a specific protein found in tooth enamel. Although less than 5% of enamel consists of protein, ameloblastins constitute 5–10% of all enamel protein, making it the second most abundant enamel matrix protein. This protein is formed by ameloblasts during the early secretory to late maturation stages of amelogenesis. Although not completely understood, the function of ameloblastins is believed to be in controlling the elongation of enamel crystals and generally directing enamel mineralization during tooth development. Ameloblastin helps in the growth of a crystalline enameloid layer consisting of randomly oriented short enamel crystals. Ameloblastin cleavage products are found in the sheath space between rod and interrod enamel, while intact ameloblastin accumulates on the enamel rods. This difference in localization is thought to maintain the boundary between rod and interrod enamel.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).