APBA1
Sign in to saveAlso known as D9S411E, LIN10, MINT1, X11, X11A, X11ALPHA, amyloid beta precursor protein binding family A member 1
Amyloid beta A4 precursor protein-binding family A member 1 is a protein that in humans is encoded by the APBA1 gene.
Gene data
APBA1- Name
- amyloid beta precursor protein binding family A member 1
- Type
- protein-coding
- Position
- 69,427,532–69,672,392 (−)
- Aliases
- D9S411E, LIN10, MINT1, X11, X11A, X11ALPHA
- Ensembl
- ENSG00000107282
- RefSeq RNA
- NM_001163.4, XM_005251968.4, XM_011518617.3, XM_017014670.2, XM_047423300.1
- RefSeq protein
- NP_001154.2, XP_005252025.1, XP_011516919.1, XP_016870159.1, XP_047279256.1
The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
amyloid beta precursor protein binding family A member 1
- Symbol
- APBA1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:69,427,532-69,672,392
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
~1 min read
Encyclopedic overview
5 sectionsContents
- Function
- Interactions
- References
- Further reading
- External links
Amyloid beta A4 precursor protein-binding family A member 1 is a protein that in humans is encoded by the APBA1 gene.
== Function ==
Excerpted from Wikipedia’s “APBA1” article, available under the CC BY-SA 4.0 licence.