APOBEC4
Sign in to saveAlso known as C1orf169, apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
C->U-editing enzyme APOBEC-4, also known as Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4, is a protein that in humans is encoded by the APOBEC4 gene. It is primarily expressed in testis and found in mammals, chicken, but not fishes.
Gene data
APOBEC4- Name
- apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
- Type
- protein-coding
- Position
- 183,646,275–183,653,316 (−)
- Aliases
- C1orf169
- Ensembl
- ENSG00000173627
- RefSeq RNA
- NM_203454.3
- RefSeq protein
- NP_982279.1
This gene encodes a member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases, which convert cytidine to uridine. Other AID/APOBEC family members are involved in mRNA editing, somatic hypermutation and recombination of immunoglobulin genes, and innate immunity to retroviral infection. [provided by RefSeq, Jul 2008].
Gene Ontology
Molecular function
via MyGene.info
Gene · Ensembl
apolipoprotein B mRNA editing enzyme catalytic polypeptide like 4
- Symbol
- APOBEC4
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:183,646,275-183,653,316
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 52415
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/403314
- genomic end
- 183622451
- genomic start
- 183646275
- chromosome
- human chromosome 1
- cytogenetic location
- 1q25.3
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Function
- References
- External links
- Further reading
C->U-editing enzyme APOBEC-4, also known as Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 4, is a protein that in humans is encoded by the APOBEC4 gene. It is primarily expressed in testis and found in mammals, chicken, but not fishes.
== Function ==
Excerpted from Wikipedia’s “APOBEC4” article, available under the CC BY-SA 4.0 licence.