APOL1
Sign in to saveAlso known as APO-L, APOL, APOL-I, FSGS4, apolipoprotein L1
protein-coding gene in the species Homo sapiens
Gene data
APOL1- Name
- apolipoprotein L1
- Type
- protein-coding
- Position
- 36,253,071–36,267,530 (+)
- Aliases
- APO-L, APOL, APOL-I, FSGS4
- Ensembl
- ENSG00000100342
- RefSeq RNA
- NM_001136540.2, NM_001136541.2, NM_001362927.2, NM_003661.4, NM_145343.3
- RefSeq protein
- NP_001130012.1, NP_001130013.1, NP_001349856.1, NP_003652.2, NP_663318.1
This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008].
Gene Ontology
Biological process
Pathways
via MyGene.info
Gene · Ensembl
apolipoprotein L1
- Symbol
- APOL1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:36,253,071-36,267,530
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- APOL1.png
Show 7 more facts
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/8542
- genomic end
- 36663576
- genomic start
- 36253071
- chromosome
- human chromosome 22
- cytogenetic location
- 22q12.3
- genetic association
- focal segmental glomerulosclerosis
via Wikidata · CC0