APOL1

Also known as APO-L, APOL, APOL-I, FSGS4, apolipoprotein L1

protein-coding gene in the species Homo sapiens

Gene data

APOL1

Name: apolipoprotein L1
Type: protein-coding
Aliases: APO-L, APOL, APOL-I, FSGS4

This gene encodes a secreted high density lipoprotein which binds to apolipoprotein A-I. Apolipoprotein A-I is a relatively abundant plasma protein and is the major apoprotein of HDL. It is involved in the formation of most cholesteryl esters in plasma and also promotes efflux of cholesterol from cells. This apolipoprotein L family member may play a role in lipid exchange and transport throughout the body, as well as in reverse cholesterol transport from peripheral cells to the liver. Several different transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008].

via MyGene.info