Arenaviridae
Sign in to saveAn arenavirus is a bi- or trisegmented ambisense RNA virus that is a member of the family Arenaviridae. These viruses infect rodents and occasionally humans. A class of novel, highly divergent arenaviruses, properly known as reptarenaviruses, have also been discovered which infect snakes to produce inclusion body disease, mostly in boa constrictors. At least eight arenaviruses are known to cause human disease. The diseases derived from arenaviruses range in severity. Aseptic meningitis, a severe human disease that causes inflammation covering the brain and spinal cord, can arise from the lymph
Species
FAMILY
- KingdomViruses
- PhylumNegarnaviricota
- ClassEllioviricetes
- OrderBunyavirales
- FamilyArenaviridae
Die Familie Arenaviridae oder Arenaviren umfasste ursprünglich nur eine Gattung Arenavirus von behüllten Viren mit einer einzelsträngigen, segmentierten ambisense-RNA als Genom. Zu den Arenaviridae gehören Erreger von Hämorrhagischem Fieber, Enzephalitis und Meningoenzephalitis beim Menschen, die durch Tiere (überwiegend Nagetiere) als natürliches Reservoir auf den Menschen übertragen werden. Die humanen Erkrankungen der Arenaviridae gehören damit zu den Zoonosen. Die neue Gattung Reptarenavirus umfasst neu isolierte Viren bei Reptilien (Boas und Pythons), die möglicherweise mit einer oft tödlich verlaufenden Infektion assoziiert sind. Der Name der Familie leitet sich vom lateinisch arenosus ‚sandig‘ bzw. arena ‚Sand‘ her, um damit die sandige ribosomale Struktur im Inneren der Virionen zu beschreiben. Die ursprüngliche Bezeichnung Arenovirus wurden wegen Verwechslungsgefahr zu Adenovirus wieder fallengelassen. Als erster Vertreter der Familie Arenaviridae wurde 1933 das Lymphozytäre-Choriomeningitis-Virus (LCMV) während einer Enzephalitis-Epidemie in St. Louis (USA) isoliert und beschrieben. Inhaltsverzeichnis 1 Morphologie 2 Biologische Eigenschaften 3 Systematik und Vorkommen 4
via GBIF
Research
5,497 papers- ICTV Virus Taxonomy Profile: Arenaviridae 2023.The Journal of general virology · 2023
- ICTV Virus Taxonomy Profile: Arenaviridae.The Journal of general virology · 2019
- The ever-expanding diversity and complexity of the Arenaviridae family.Virulence · 2023
- Brothers in Arms: Structure, Assembly and Function of Arenaviridae Nucleoprotein.Viruses · 2020
- A structural perspective on the evolution of viral/cellular macromolecular complexes within the arenaviridae family of viruses.Current opinion in structural biology · 2023
via PubMed
Wikidata facts
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- topic's main category
- Category:Arenaviridae
- taxon name
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- Commons category
- Arenaviridae
- ICTV virus genome composition
- negative-sense single strand RNA virus
Sources (1)
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Encyclopedic overview
20 sectionsContents
- Structure
- Genome
- Microbiology
- Taxonomy
- ''Mammarenavirus''
- Old World complex
- New World complex
- ''Reptarenavirus''
- ''Hartmanivirus''
- Antennavirus
- Evolution
- Reservoirs
- Epidemiology
- Hosts
- Clinical diseases
- Recent outbreaks
- Treatments
- Experimental approaches
- References
- External links
An arenavirus is a bi- or trisegmented ambisense RNA virus that is a member of the family Arenaviridae. These viruses infect rodents and occasionally humans. A class of novel, highly divergent arenaviruses, properly known as reptarenaviruses, have also been discovered which infect snakes to produce inclusion body disease, mostly in boa constrictors. At least eight arenaviruses are known to cause human disease. The diseases derived from arenaviruses range in severity. Aseptic meningitis, a severe human disease that causes inflammation covering the brain and spinal cord, can arise from the lymphocytic choriomeningitis virus. Hemorrhagic fever syndromes, including Lassa fever, are derived from infections such as Guanarito virus, Junin virus, Lassa virus, Lujo virus, Machupo virus, Sabia virus, or Whitewater Arroyo virus. Because of the epidemiological association with rodents, some arenaviruses and bunyaviruses are designated as roboviruses.
==Structure== thumb|Mammarenavirus structure and genome composition. Viewed in cross-section, arenaviruses contain grainy particles that are ribosomes acquired from their host cells. It is from this characteristic that they acquired the name arena, from the Latin root meaning sand. The ribosomal structures are not believed to be essential for virus replication. Virus particles, or virions, are pleomorphic (variable in shape) but are often spherical, with a diameter of 60–300 nm, and are covered with surface glycoprotein spikes.
Excerpted from Wikipedia’s “Arenaviridae” article, available under the CC BY-SA 4.0 licence.