The human ARHGEF10 gene encodes the protein Rho guanine nucleotide exchange factor 10.
This gene encodes a Rho guanine nucleotide exchange factor (GEF). Rho GEFs regulate the activity of small Rho GTPases by stimulating the exchange of guanine diphosphate (GDP) for guanine triphosphate (GTP) and may play a role in neural morphogenesis. Mutations in this gene are associated with slowed nerve conduction velocity (SNCV). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015].
via MyGene.info
The human ARHGEF10 gene encodes the protein Rho guanine nucleotide exchange factor 10.
Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).