Structure via PubChem · Public domain (PubChem)
azvudine
Sign in to saveAlso known as 2′-deoxy-2′-β-fluoro-4′-azidocytidine
Azvudine is an antiviral drug which acts as a reverse transcriptase inhibitor. It was discovered for the treatment of hepatitis C and has since been investigated for use against other viral diseases such as AIDS and COVID-19, for which it was granted conditional approval in China.
Chemical data
- Formula
- C9H11FN6O4
- Molecular weight
- 286.22 g/mol
- IUPAC name
- 4-amino-1-[(2R,3S,4R,5R)-5-azido-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
- SMILES
- C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@](O2)(CO)N=[N+]=[N-])O)F
- InChIKey
- KTOLOIKYVCHRJW-XZMZPDFPSA-N
- XLogP
- -0.8
- Polar surface area
- 123 Ų
- H-bond donors
- 3
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 286.082581052
Show 4 more facts
- isomeric SMILES
- C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@](O2)(CO)N=[N+]=[N-])O)F
- chemical formula
- C₉H₁₁FN₆O₄
- Commons category
- Azvudine
- canonical SMILES
- C1=CN(C(=O)N=C1N)C2C(C(C(O2)(CO)N=[N+]=[N-])O)F
Sources (1)
via Wikidata · CC0
~6 min read
Encyclopedic overview
7 sectionsContents
- Medical uses
- Adverse effects
- Non-human models
- History
- Society and culture
- References
- Further reading
Azvudine is an antiviral drug which acts as a reverse transcriptase inhibitor. It was discovered for the treatment of hepatitis C and has since been investigated for use against other viral diseases such as AIDS and COVID-19, for which it was granted conditional approval in China.
Azvudine was first discovered in 2007. It costs 350 Chinese yuan per 7 days for COVID, .
Excerpted from Wikipedia’s “azvudine” article, available under the CC BY-SA 4.0 licence.