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bamlanivimab

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Also known as LY3819253, LY-CoV555

Bamlanivimab is a monoclonal antibody developed by AbCellera Biologics and Eli Lilly as a treatment for COVID-19. The medication was granted an emergency use authorization (EUA) by the US Food and Drug Administration (FDA) in November 2020, and the EUA was revoked in April 2021.

Key facts

Drug.type
mab
Drug.mab_type
mab
Drug.source
u
Drug.target
Spike protein of SARS-CoV-2
Drug.DailyMedID
Bamlanivimab
Drug.routes_of_administration
Intravenous
Drug.ATC_prefix
None
Drug.legal_CA
Rx-only
Drug.legal_CA_comment
/ Schedule D
Drug.legal_US
Rx-only
Drug.legal_US_comment
via emergency use authorization
Drug.CAS_number
2423943-37-5
Drug.DrugBank
DB15718
Drug.UNII
45I6OFJ8QH
Drug.KEGG
D11936
Drug.synonyms
LY-CoV555, LY3819253

via Wikipedia infobox

~5 min read

Encyclopedic overview

12 sections
Contents
  • Studies
  • Animal trials
  • Human trials
  • BLAZE-1 Trial
  • ACTIV-2 Trial
  • ACTIV-3 Trial
  • Authorization
  • Bamlanivimab/etesevimab
  • Deployment
  • Society and culture
  • Names
  • References

Bamlanivimab is a monoclonal antibody developed by AbCellera Biologics and Eli Lilly as a treatment for COVID-19. The medication was granted an emergency use authorization (EUA) by the US Food and Drug Administration (FDA) in November 2020, and the EUA was revoked in April 2021.

Bamlanivimab is an IgG1 monoclonal antibody (mAb) directed against the spike protein of SARS-CoV-2. The aim is to block viral attachment and entry into human cells, thus neutralizing the virus, and help preventing and treating COVID-19.

Excerpted from Wikipedia’s “bamlanivimab” article, available under the CC BY-SA 4.0 licence.