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bezlotoxumab

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Bezlotoxumab, sold under the brand name Zinplava, is a human monoclonal antibody designed for the prevention of recurrence of Clostridioides difficile infections. Bezlotoxumab binds to Clostridioides difficile toxin B.

Key facts

Drug.H
9974
Drug.type
mab
Drug.mab_type
mab
Drug.source
u
Drug.target
Clostridioides difficile toxin B
Drug.tradename
Zinplava
Drug.MedlinePlus
a617003
Drug.DailyMedID
Bezlotoxumab
Drug.pregnancy_AU
B2
Drug.routes_of_administration
Intravenous
Drug.ATC_prefix
J06
Drug.ATC_suffix
BC03
Drug.legal_AU
S4
Drug.legal_UK
POM
Drug.legal_US
Rx-only
Drug.legal_EU
Rx-only
Drug.CAS_number
1246264-45-8
Drug.DrugBank
DB13140

via Wikipedia infobox

Wikidata facts

Has use
medication
Show 1 more fact
subject has role
monoclonal antibody

via Wikidata · CC0

~4 min read

Encyclopedic overview

4 sections
Contents
  • Medical uses
  • Mechanism of TcdB neutralization
  • History
  • References

Bezlotoxumab, sold under the brand name Zinplava, is a human monoclonal antibody designed for the prevention of recurrence of Clostridioides difficile infections. Bezlotoxumab binds to Clostridioides difficile toxin B.

== Medical uses == Bezlotoxumab is indicated to reduce recurrence of Clostridioides difficile infection in people who are receiving antibacterial drug treatment for Clostridioides difficile infection and are at a high risk for Clostridioides difficile infection recurrence.

Excerpted from Wikipedia’s “bezlotoxumab” article, available under the CC BY-SA 4.0 licence.