Structure via PubChem · Public domain (PubChem)
benzthiazide
Sign in to saveAlso known as Aquatag®, Fovane®, 3-benzylthiomethyl-6-chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide, 6-chloro-1,1-dioxo-3-(phenylmethylsulfanylmethyl)-4H-benzo[e][1,2,4]thiadiazine-7-sulfonamide, 3-((benzylthio)methyl)-6-chloro-7-sulfamoyl-2H-benzo-1,2,4-thiadiazine 1,1-dioxide, 3-benzylthiomethyl-6-chloro-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide, 6-chloro-7-sulfamoyl-3-benzylthiomethyl-2H-1,2,4-benzothiadiazine 1,1-dioxide, benzothiazide
Benzthiazide (BAN/INN, also known as benzothiazide; trade names Aquatag, Dihydrex, Diucen, Edemax, Exna, Foven and others) is a thiazide diuretic used in the treatment of high blood pressure and edema. It is no longer available in the United States.
Chemical data
- Formula
- C15H14ClN3O4S3
- Molecular weight
- 431.9 g/mol
- IUPAC name
- 3-(benzylsulfanylmethyl)-6-chloro-1,1-dioxo-4H-1lambda6,2,4-benzothiadiazine-7-sulfonamide
- SMILES
- C1=CC=C(C=C1)CSCC2=NS(=O)(=O)C3=CC(=C(C=C3N2)Cl)S(=O)(=O)N
- InChIKey
- NDTSRXAMMQDVSW-UHFFFAOYSA-N
- XLogP
- 1.7
- Polar surface area
- 161 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1960
- Admin. routes
- oral
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 430.983497
- Has use
- medication
Show 6 more facts
- chemical formula
- C₁₅H₁₄ClN₃O₄S₃
- subject has role
- carbonic anhydrase inhibitor
- medical condition treated
- arterial hypertension
- canonical SMILES
- C1=CC=C(C=C1)CSCC2=NS(=O)(=O)C3=CC(=C(C=C3N2)Cl)S(=O)(=O)N
- World Health Organisation international non-proprietary name
- benzthiazide
- Commons category
- Benzthiazide
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Benzthiazide (BAN/INN, also known as benzothiazide; trade names Aquatag, Dihydrex, Diucen, Edemax, Exna, Foven and others) is a thiazide diuretic used in the treatment of high blood pressure and edema. It is no longer available in the United States.
In the United Kingdom, it was also sold in combination with the potassium-sparing diuretic triamterene under the trade name Dytide. The same combination is still available in Switzerland as Dyrenium compositum.
Excerpted from Wikipedia’s “benzthiazide” article, available under the CC BY-SA 4.0 licence.