Structure via PubChem · Public domain (PubChem)
bergaptene
Sign in to saveAlso known as 5-methoxypsoralene, Majudin, Heraclin, 4-methoxy-7H-furo[3,2-g][1]benzopyran-7-one, 4-methoxyfuro[3,2-g]chromen-7-one, 4-methoxy-7-furo[3,2-g][1]benzopyranone, 5-methoxypsoralen
farmaco
Chemical data
- Formula
- C12H8O4
- Molecular weight
- 216.19 g/mol
- IUPAC name
- 4-methoxyfuro[3,2-g]chromen-7-one
- SMILES
- COC1=C2C=CC(=O)OC2=CC3=C1C=CO3
- InChIKey
- BGEBZHIAGXMEMV-UHFFFAOYSA-N
- XLogP
- 2.3
- Polar surface area
- 48.7 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- atopic eczema, psoriasis
via ChEMBL · EBI
Research
882 papers- Bergapten inhibits NLRP3 inflammasome activation and pyroptosis via promoting mitophagy.Acta pharmacologica Sinica · 2023
- Bergapten: A review of its pharmacology, pharmacokinetics, and toxicity.Phytotherapy research : PTR · 2021
- Bergapten ameliorates combined allergic rhinitis and asthma syndrome after PM2.5 exposure by balancing Treg/Th17 expression and suppressing STAT3 and MAPK activation in a mouse model.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2023
- Natural small molecule bergapten ameliorates rheumatoid arthritis by targeting STAT3.Pharmacological research · 2025
- Inhalable and bioactive lipid-nanomedicine based on bergapten for targeted acute lung injury therapy via orchestrating macrophage polarization.Bioactive materials · 2025
via PubMed
Wikidata facts
- Subclass of
- furanocoumarin
- Mass
- 216.042259
Show 5 more facts
- chemical formula
- C₁₂H₈O₄
- canonical SMILES
- COC1=C2C=CC(=O)OC2=CC3=C1C=CO3
- subject has role
- carcinogen
- Commons category
- Bergapten
- has characteristic
- bitterness
via Wikidata · CC0
Article · Italiano
Il bergaptene (5-metossipsoralene) è una sostanza appartenente alla famiglia degli psoraleni (molecole note anche con il nome di furocumarine lineari), che si trova principalmente nell'olio essenziale di bergamotto (l'essenza ne contiene in genere tra lo 0,4 e lo 0,7%) e in molti altri oli essenziali agrumari. È una sostanza . Viene utilizzato nella cura di alcune forme di psoriasi.
Abstract from DBpedia / Wikipedia · CC BY-SA