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bexlosteride

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Bexlosteride is a potent and noncompetitive inhibitor of the enzyme 5α-reductase related to finasteride and dutasteride. It is selective for the type I isoform of the enzyme. It advanced to Phase III clinical trials, but development was halted at that stage, and it was never marketed.

Wikidata facts

Mass
249.092
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chemical formula
C₁₄H₁₆ClNO
isomeric SMILES
CN1[C@@H]2CCC3=C([C@H]2CCC1=O)C=CC(=C3)Cl
canonical SMILES
CN1C2CCC3=C(C2CCC1=O)C=CC(=C3)Cl
Commons category
Bexlosteride
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Contents
  • Synthesis
  • See also
  • References

Bexlosteride is a potent and noncompetitive inhibitor of the enzyme 5α-reductase related to finasteride and dutasteride. It is selective for the type I isoform of the enzyme. It advanced to Phase III clinical trials, but development was halted at that stage, and it was never marketed.

==Synthesis== The synthesis of Bexlosteride has been reported in the literature.

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