biricodar
Sign in to saveBiricodar (INN, codename VX-710, brand name Incel) was a pharmaceutical drug under development by Vertex Pharmaceuticals to help treat antineoplastic resistance in cancer.
Wikidata facts
- Mass
- 603.294
Show 3 more facts
- chemical formula
- C₃₄H₄₁N₃O₇
- canonical SMILES
- COC1=CC(=CC(=C1OC)OC)C(=O)C(=O)N2CCCCC2C(=O)OC(CCCC3=CN=CC=C3)CCCC4=CN=CC=C4
- isomeric SMILES
- COC1=CC(=CC(=C1OC)OC)C(=O)C(=O)N2CCCC[C@H]2C(=O)OC(CCCC3=CN=CC=C3)CCCC4=CN=CC=C4
via Wikidata · CC0
~2 min read
Article
5 sectionsContents
- History
- Synthesis
- Mechanism
- References
- Further reading
Biricodar (INN, codename VX-710, brand name Incel) was a pharmaceutical drug under development by Vertex Pharmaceuticals to help treat antineoplastic resistance in cancer.
Biricodar is considered a second-generation ABC transporter inhibitor and has been described as one of the most famous foundational drugs of this class. Although it has not been brought to market, biricodar continues to be used in basic research and is a compound of interest for potential clinical applications.
Connections
cancer
Entity
medication
Entity
International Standard Book Number
Entity
base
Entity
digital object identifier
Entity
chemical formula
Entity
chemotherapy
Entity
alkyne
Entity
carboxylic acid
Entity
ester
Entity
molar mass
Entity
Q180686
Entity
amides
Entity
CAS Registry Number
Entity
pyridine
Entity
Q229883
Entity
PubChem
Entity
Anatomical Therapeutic Chemical Classification System
Entity
hydrogenation
Entity
basic research
Entity