Botulismus

Also known as Botulism poisoning, Food poisoning due to Clostridium botulinum, Foodborne botulism, Infection due to clostridium botulinum, Intoxication with Clostridium botulinum toxin, Wound botulism (subtype), Infant botulism (subtype), Botulism

Erkrankung durch das Bakterientoxin von Clostridium botulinum

AI overview

Botulism is a rare but potentially deadly illness caused by a toxin produced by a specific bacterium that typically starts with weakness, blurred vision, and fatigue before progressing to affect the arms, chest, and legs. The disease matters because it can be serious enough to be life-threatening, though it generally does not cause fever or loss of consciousness.

AI-generated from the Wikipedia summary — may contain errors.

Key facts

Medical condition (new).caption: A 14-year-old boy with botulism, characterised by weakness of the eye muscles and the drooping eyelids shown in the left image, and dilated and non-moving pupils shown in the right image. This person was fully conscious.
Medical condition (new).field: Infectious disease, gastroenterology
Medical condition (new).symptoms: Weakness, trouble seeing, feeling tired, trouble speaking
Medical condition (new).complications: Respiratory failure
Medical condition (new).onset: 12 to 72 hours
Medical condition (new).duration: Variable
Medical condition (new).types: Foodborne, wound, infant, adult intestinal toxemia, inhalational, iatrogenic
Medical condition (new).causes: Clostridium botulinum
Medical condition (new).risks: Improperly canned, preserved or fermented foods; injection drug use (e.g. black-tar heroin); honey consumption in infants <1 year; contaminated wounds; high-dose cosmetic/therapeutic botulinum-toxin injections
Medical condition (new).diagnosis: Finding the bacteria or their toxin
Medical condition (new).differential: Myasthenia gravis, Guillain–Barré syndrome, Amyotrophic lateral sclerosis, Lambert Eaton syndrome
Medical condition (new).prevention: Proper food preparation, no honey for children younger than one
Medical condition (new).treatment: Antitoxin, antibiotics, mechanical ventilation
Medical condition (new).prognosis: ~7.5% risk of death
Medical condition (new).frequency: Worldwide: c. 1 000 reported cases per year; United States: 273 cases in 2021
Medical condition (new).deaths: Global case-fatality rate 5–10 % (≈50–100 deaths annually)
Medical condition (new).name: Botulism
Medical condition (new).image: Botulism1and2.JPG

via Wikipedia infobox

Research

4,766 papers

Clinical Guidelines for Diagnosis and Treatment of Botulism, 2021.MMWR. Recommendations and reports : Morbidity and mortality weekly report. Recommendations and reports · 2021Rao AK, Sobel J, Chatham-Stephens K et al.DOI: 10.15585/mmwr.rr7002a1
Botulism.ReviewClinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2005Sobel JDOI: 10.1086/444507
Botulism in fish: a review.ReviewJournal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024Uzal FA, Henderson E, Asin JDOI: 10.1177/10406387241236725
Botulism.ReviewPediatrics in review · 2016Carrillo-Marquez MADOI: 10.1542/pir.2015-0018
Human Botulism in France, 1875-2016.ReviewToxins · 2020Rasetti-Escargueil C, Lemichez E, Popoff MRDOI: 10.3390/toxins12050338
Botulism.ReviewSeminars in neurology · 1990Cherington MDOI: 10.1055/s-2008-1041249
[Infant botulism].ReviewHarefuah · 2014Falk A, Afriat A, Hubary Y et al.
Clostridial Diseases (Botulism and Tetanus).ReviewThe Veterinary clinics of North America. Equine practice · 2022Swink JM, Gilsenan WFDOI: 10.1016/j.cveq.2022.05.004

via PubMed

Wikidata facts

Subclass of: foodborne illness
Image: Clostridium botulinum.jpg

Show 15 more facts

possible treatment: mechanical ventilation
topic's main category: Category:Botulism
NCI Thesaurus ID: C84599
health specialty: infectious diseases
Commons category: Botulism
ICPC 2 ID: D70
exact match: www.orpha.net/ORDO/Orphanet_1267
minimal incubation period in humans: 6
maximal incubation period in humans: 10
on focus list of Wikimedia project: Wikipedia:Vital articles/Level/4
WordLift URL: data.medicalrecords.com/medicalrecords/healthwise/botulism_2
symptoms and signs: acute respiratory insufficiency
has cause: botulinum toxin group
has natural reservoir: soil
maintained by WikiProject: WikiProject Food and drink

Sources (11)

via Wikidata · CC0

Article · Deutsch

Botulismus (von lateinisch botulus ‚Wurst‘), auch Fleischvergiftung, Wurstvergiftung oder Allantiasis (von altgriechisch ἀλλᾶς ‚Wurst‘) genannt, ist eine lebensbedrohliche Vergiftung, die von Botulinumtoxin (auch Botulismus-Toxin) verursacht wird. Dieser Giftstoff wird vom Bakterium Clostridium botulinum, das 1896 in Schinkenresten durch den Bakteriologen Emile van Ermengem als Verursacher nachgewiesen wurde, produziert. Meist wird die durch Lähmungen der Augenmuskeln und bulbären Zentren (vgl. Bulbärhirnsyndrom) charakterisierte Vergiftung durch verdorbenes Fleisch (auch Fisch und Wurst) oder nicht fachgerecht eingekochtes Gemüse hervorgerufen. In der Lebensmittelherstellung wird das Wachstum des Bakteriums durch Pökeln oder Hitzesterilisation verhindert. Man unterscheidet zwischen der Erkrankung beim Menschen und beim Rind. Die Inkubationszeit (Ausbruchszeit nach der Infektion) beträgt beim Menschen in der Regel 12 bis 36 Stunden, kann aber auch kürzer oder länger sein, d. h. zwischen zwei Stunden und 14 Tagen liegen.

Abstract from DBpedia / Wikipedia · CC BY-SA