Gene data
C1QA- Name
- complement C1q A chain
- Type
- protein-coding
- Position
- 22,635,057–22,640,201 (+)
- Aliases
- C1QD1
- Ensembl
- ENSG00000173372
- RefSeq RNA
- NM_001347465.2, NM_001347466.2, NM_015991.4
- RefSeq protein
- NP_001334394.1, NP_001334395.1, NP_057075.1
This gene encodes the A-chain polypeptide of serum complement subcomponent C1q, which associates with C1r and C1s to yield the first component of the serum complement system. C1q deficiency is associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains which include 6 A-chains, 6 B-chains, and 6 C-chains. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016].
Gene Ontology
Biological process
Molecular function
Pathways
Complement and coagulation cascades - Homo sapiens (human)Prion disease - Homo sapiens (human)Pertussis - Homo sapiens (human)Chagas disease - Homo sapiens (human)Staphylococcus aureus infection - Homo sapiens (human)Coronavirus disease - COVID-19 - Homo sapiens (human)Systemic lupus erythematosus - Homo sapiens (human)DiseaseComplement cascadeInitial triggering of complement
via MyGene.info
Gene · Ensembl
complement C1q A chain
- Symbol
- C1QA
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:22,635,057-22,640,201
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Complement c1q subcomponent subunit A 1PK6.png
Show 8 more facts
- HomoloGene ID
- 7249
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/712
- genomic start
- 22635077
- chromosome
- human chromosome 1
- genomic end
- 22639678
- cytogenetic location
- 1p36.12
- expressed in
- gastric mucosa
Sources (3)
via Wikidata · CC0