CABIN1
Sign in to saveAlso known as CAIN, PPP3IN, KB-318B8.7, calcineurin binding protein 1
Calcineurin-binding protein cabin-1 is a protein that in humans is encoded by the CABIN1 gene.
Gene data
CABIN1- Name
- calcineurin binding protein 1
- Type
- protein-coding
- Position
- 24,011,192–24,178,634 (+)
- Aliases
- CAIN, KB-318B8.7, PPP3IN
- Ensembl
- ENSG00000099991
- RefSeq RNA
- NM_001199281.1, NM_001201429.2, NM_012295.4, XM_005261415.4, XM_005261416.4
- RefSeq protein
- NP_001186210.1, NP_001188358.1, NP_036427.1, XP_005261472.1, XP_005261473.1
Calcineurin plays an important role in the T-cell receptor-mediated signal transduction pathway. The protein encoded by this gene binds specifically to the activated form of calcineurin and inhibits calcineurin-mediated signal transduction. The encoded protein is found in the nucleus and contains a leucine zipper domain as well as several PEST motifs, sequences which confer targeted degradation to those proteins which contain them. Alternative splicing results in multiple transcript variants encoding two different isoforms. [provided by RefSeq, Jan 2011].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
calcineurin binding protein 1
- Symbol
- CABIN1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 22:24,011,192-24,178,634
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein CABIN1 PDB 1n6j.png
Show 5 more facts
- HomoloGene ID
- 49307
- exact match
- identifiers.org/ncbigene/23523
- genomic start
- 24407642
- genomic end
- 24574596
- cytogenetic location
- 22q11.23
Sources (3)
via Wikidata · CC0
~1 min read
Article
5 sectionsContents
- Function
- Interactions
- References
- Further reading
- External links
Calcineurin-binding protein cabin-1 is a protein that in humans is encoded by the CABIN1 gene.
== Function ==