CACYBP
Sign in to saveAlso known as GIG5, S100A6BP, SIP, PNAS-107, calcyclin binding protein
Calcyclin-binding protein is a protein that in humans is encoded by the CACYBP gene.
Gene data
CACYBP- Name
- calcyclin binding protein
- Type
- protein-coding
- Position
- 174,999,163–175,022,285 (+)
- Aliases
- GIG5, PNAS-107, S100A6BP, SIP
- Ensembl
- ENSG00000116161
- RefSeq RNA
- NM_001007214.1, NM_014412.3
- RefSeq protein
- NP_001007215.1, NP_055227.1
The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
calcyclin binding protein
- Symbol
- CACYBP
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 1:174,999,163-175,022,285
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CACYBP PDB 1x5m.png
Show 7 more facts
- HomoloGene ID
- 7649
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/27101
- genomic end
- 175012027
- genomic start
- 174968300
- chromosome
- human chromosome 1
- cytogenetic location
- 1q25.1
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- Protein Interactions
- References
- External links
- Further reading
Calcyclin-binding protein is a protein that in humans is encoded by the CACYBP gene.
The protein encoded by this gene is a calcyclin binding protein. It may be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It probably serves as a molecular bridge in ubiquitin E3 complexes and participates in the ubiquitin-mediated degradation of beta-catenin. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Excerpted from Wikipedia’s “CACYBP” article, available under the CC BY-SA 4.0 licence.