Caldesmon 1
Sign in to saveAlso known as CDM, HCAD, L-CAD, testis secretory sperm-binding protein Li 227n, CALD1, NAG22, H-CAD, caldesmon
Caldesmon is a protein that in humans is encoded by the CALD1 gene.
Protein · UniProt
Caldesmon
- Gene
- CALD1
- Organism
- Homo sapiens (Human)
- Length
- 793 aa
- Molecular mass
- 93,231 Da
- Evidence
- 1: Evidence at protein level
Actin- and myosin-binding protein implicated in the regulation of actomyosin interactions in smooth muscle and nonmuscle cells (could act as a bridge between myosin and actin filaments). Stimulates actin binding of tropomyosin which increases the stabilization of actin filament structure. In muscle tissues, inhibits the actomyosin ATPase by binding to F-actin. This inhibition is attenuated by calcium-calmodulin and is potentiated by tropomyosin. Interacts with actin, myosin, two molecules of tropomyosin and with calmodulin. Also plays an essential role during cellular mitosis and receptor c…
Swiss-Prot (reviewed) · via UniProt
~1 min read
Encyclopedic overview
4 sectionsContents
- Immunochemistry
- References
- Further reading
- External links
Caldesmon is a protein that in humans is encoded by the CALD1 gene.
Caldesmon is a calmodulin binding protein. Like calponin, caldesmon tonically inhibits the ATPase activity of myosin in smooth muscle.
Excerpted from Wikipedia’s “Caldesmon 1” article, available under the CC BY-SA 4.0 licence.