Structure via PubChem · Public domain (PubChem)
calycosin
Sign in to saveAlso known as 3'-hydroxy-formononetin, 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one, 7-Hydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-one
Calycosin is an O-methylated isoflavone. It can be isolated from Astragalus membranaceus Bge. var. mongholicus and Trifolium pratense L. (red clover).
Chemical data
- Formula
- C16H12O5
- Molecular weight
- 284.26 g/mol
- IUPAC name
- 7-hydroxy-3-(3-hydroxy-4-methoxyphenyl)chromen-4-one
- SMILES
- COC1=C(C=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)O)O
- InChIKey
- ZZAJQOPSWWVMBI-UHFFFAOYSA-N
- XLogP
- 2.4
- Polar surface area
- 76 Ų
- H-bond donors
- 2
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- isoflavone
- Mass
- 284.068473
Show 4 more facts
- found in taxon
- Propolis
- chemical formula
- C₁₆H₁₂O₅
- canonical SMILES
- COC1=C(C=C(C=C1)C2=COC3=C(C2=O)C=CC(=C3)O)O
- Commons category
- Calycosin
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Biosynthesis
- Pharmacology
- References
Calycosin is an O-methylated isoflavone. It can be isolated from Astragalus membranaceus Bge. var. mongholicus and Trifolium pratense L. (red clover).
== Biosynthesis == Isoflavone 3′-hydroxylase uses formononetin, NADPH, H+ and O2 to produce calycosin, NADP+ and H2O.
Excerpted from Wikipedia’s “calycosin” article, available under the CC BY-SA 4.0 licence.