Structure via PubChem · Public domain (PubChem)
coronaridine
Sign in to saveAlso known as (-)-coronaridine
Coronaridine, also known as 18-carbomethoxyibogamine, is an alkaloid found in Tabernanthe iboga and related species, including Tabernaemontana divaricata for which (under the now obsolete synonym Ervatamia coronaria) it was named.
Chemical data
- Formula
- C21H26N2O2
- Molecular weight
- 338.4 g/mol
- IUPAC name
- methyl (1S,15S,17S,18S)-17-ethyl-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraene-1-carboxylate
- SMILES
- CC[C@H]1C[C@H]2C[C@@]3([C@H]1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC
- InChIKey
- NVVDQMVGALBDGE-KSWFMABOSA-N
- XLogP
- 3.5
- Polar surface area
- 45.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 338.199
Show 5 more facts
- found in taxon
- Rauvolfia verticillata
- canonical SMILES
- CCC1CC2CC3(C1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC
- chemical formula
- C₂₁H₂₆N₂O₂
- isomeric SMILES
- CC[C@H]1C[C@H]2C[C@@]3([C@H]1N(C2)CCC4=C3NC5=CC=CC=C45)C(=O)OC
- Commons category
- Coronaridine
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
6 sectionsContents
- Chemistry
- Congeners
- Pharmacology
- Sources
- See also
- References
Coronaridine, also known as 18-carbomethoxyibogamine, is an alkaloid found in Tabernanthe iboga and related species, including Tabernaemontana divaricata for which (under the now obsolete synonym Ervatamia coronaria) it was named.
Like ibogaine, (R)-coronaridine and (S)-coronaridine can decrease intake of cocaine and morphine in animals and it may have muscle relaxant and hypotensive activity.
Excerpted from Wikipedia’s “coronaridine” article, available under the CC BY-SA 4.0 licence.