carbadox

Carbadox is a veterinary drug that combats infection in swine, particularly swine dysentery.

Chemical data

Formula: C11H10N4O4
Molecular weight: 262.22 g/mol
IUPAC name: methyl N-[(1,4-dioxidoquinoxaline-1,4-diium-2-yl)methylideneamino]carbamate

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Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

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Research

324 papers

The In-Feed Antibiotic Carbadox Induces Phage Gene Transcription in the Swine Gut Microbiome.mBio · 2017
The metabolism of carbadox, olaquindox, mequindox, quinocetone and cyadox: an overview.Medicinal chemistry (Shariqah (United Arab Emirates)) · 2013
Carbadox has both temporary and lasting effects on the swine gut microbiota.Frontiers in microbiology · 2014
The agricultural antibiotic carbadox induces phage-mediated gene transfer in Salmonella.Frontiers in microbiology · 2014
Some pharmacokinetic observations of carbadox medication in pigs.The veterinary quarterly · 1988

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Wikidata facts

Mass: 262.0702048

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canonical SMILES: COC(=O)NN=Cc1c[n+](c2ccccc2[n+]1[O-])[O-]
chemical formula: C₁₁H₁₀N₄O₄

Sources (2)

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~2 min read

Article

4 sections

Contents

Indications
Safety
Regulation
References

Carbadox is a veterinary drug that combats infection in swine, particularly swine dysentery.

==Indications== Carbadox is indicated for control of swine dysentery (vibrionic dysentery, bloody scours, or hemorrhagic dysentery); control of bacterial swine enteritis (salmonellosis or necrotic enteritis caused by Salmonella enterica); aid in the prevention of migration and establishment of large roundworm (Ascaris suum) infections; aid in the prevention of establishment of nodular worm (Oesophagostomum) infections.