CBR3
Sign in to saveAlso known as HEL-S-25, SDR21C2, hCBR3, carbonyl reductase 3
Carbonyl reductase [NADPH] 3 is an enzyme that in humans is encoded by the CBR3 gene.
Gene data
CBR3- Name
- carbonyl reductase 3
- Type
- protein-coding
- Position
- 36,135,042–36,146,569 (+)
- Aliases
- HEL-S-25, SDR21C2, hCBR3
- Ensembl
- ENSG00000159231
- RefSeq RNA
- NM_001236.4, XM_011529772.3, XM_054324909.1
- RefSeq protein
- NP_001227.1, XP_011528074.1, XP_054180884.1
Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
carbonyl reductase 3
- Symbol
- CBR3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 21:36,135,042-36,146,569
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CBR3 PDB 2hrb.png
Show 8 more facts
- HomoloGene ID
- 20332
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/874
- genomic end
- 36146562
- genomic start
- 36135079
- chromosome
- human chromosome 21
- cytogenetic location
- 21q22.12
- expressed in
- Achilles tendon
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Carbonyl reductase [NADPH] 3 is an enzyme that in humans is encoded by the CBR3 gene.
Carbonyl reductase 3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. The enzyme is classified as a monomeric NADPH-dependent oxidoreductase. CBR3 contains three exons spanning 11.2 kilobases and is closely linked to another carbonyl reductase gene - CBR1.
Excerpted from Wikipedia’s “CBR3” article, available under the CC BY-SA 4.0 licence.