Key facts
- Length bp
- 45,090,682 bp, (CHM13)
- Number span no of genes
- 215 ( CCDS )
- Type
- Autosome
- Centromere position
- Acrocentric , (12.0 Mbp )
- Ccds
- Gene list
- Hgnc
- Gene list
- Uniprot
- Gene list
- Ncbi
- Gene list
- Ensembl
- Chromosome 21
- Entrez
- Chromosome 21
- Ucsc
- Chromosome 21
- Refseq
- NC_000021 ( FASTA )
- Genbank
- CM000683 ( FASTA )
via Wikipedia infobox
Research
5,170 papers- Human chromosome 21: genome mapping and exploration, circa 1993.Trends in genetics : TIG · 1993
- Molecular genetics of human chromosome 21.Journal of medical genetics · 1987
- Structure of human chromosome 21--for an understanding of genetic diseases including Down's syndrome.Bioscience, biotechnology, and biochemistry · 1997
- Isolation and characterization of DNA probes for human chromosome 21.Progress in clinical and biological research · 1990
- The sequence of human chromosome 21 and implications for research into Down syndrome.Genome biology · 2000
via PubMed
Wikidata facts
- Instance of
- chromosome
- Subclass of
- acrocentric chromosome
- Part of
- human genome
- Followed by
- human chromosome 22
- Follows
- human chromosome 20
- Length
- 46709983
Show 4 more facts
- Commons category
- Human chromosome 21
- found in taxon
- Homo sapiens
- short name
- 21
- genetic association
- Down syndrome
via Wikidata · CC0
~17 min read
Encyclopedic overview
Chromosome 21 is one of the 23 pairs of chromosomes in humans. Chromosome 21 is both the smallest human autosome and chromosome, with 46.7 million base pairs (the building material of DNA) representing about 1.5 percent of the total DNA in cells. Most people have two copies of chromosome 21, while those with three copies of chromosome 21 (trisomy 21) have Down syndrome.
Researchers working on the Human Genome Project announced in May 2000 that they had determined the sequence of base pairs that make up this chromosome. Chromosome 21 was the second human chromosome to be fully sequenced, after chromosome 22.
Excerpted from Wikipedia’s “human chromosome 21” article, available under the CC BY-SA 4.0 licence.