CBY1

Also known as C22orf2, CBY, HS508I15A, PGEA1, PIGEA-14, PIGEA14, arb1, chibby homolog 1 (Drosophila)

protein-coding gene in the species Homo sapiens

Gene data

CBY1

Name: chibby 1, beta catenin antagonist
Type: protein-coding
Aliases: C22orf2, CBY, Chibby1, HS508I15A, PGEA1, PIGEA-14, PIGEA14, arb1

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

via MyGene.info