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GeneQ18037681· pop 5· linked from 6 articles

Also known as C22orf2, CBY, HS508I15A, PGEA1, PIGEA-14, PIGEA14, arb1, chibby homolog 1 (Drosophila)

protein-coding gene in the species Homo sapiens

Gene data

CBY1
Name
chibby 1, beta catenin antagonist
Type
protein-coding
Aliases
C22orf2, CBY, Chibby1, HS508I15A, PGEA1, PIGEA-14, PIGEA14, arb1

Beta-catenin is a transcriptional activator and oncoprotein involved in the development of several cancers. The protein encoded by this gene interacts directly with the C-terminal region of beta-catenin, inhibiting oncogenic beta-catenin-mediated transcriptional activation by competing with transcription factors for binding to beta-catenin. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

via MyGene.info

Wikidata facts

Show 5 more facts
HomoloGene ID
12514
genomic end
38673854
genomic start
39052641
cytogenetic location
22q13.1
Sources (3)

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