Structure via PubChem · Public domain (PubChem)
carbonil cianuro m-clorofenil idrazone
Sign in to saveAlso known as [(3-chlorophenyl)hydrazono]propanedinitrile, carbonylcyanide-3-chlorophenylhydrazone, [(3-chlorophenyl)hydrazono]malononitrile, (3-chlorophenyl)hydrazonomalononitrile, carbonyl cyanide m-chlorophenyl hydrazone
farmaco
Chemical data
- Formula
- C9H5ClN4
- Molecular weight
- 204.61 g/mol
- IUPAC name
- 2-[(3-chlorophenyl)hydrazinylidene]propanedinitrile
- SMILES
- C1=CC(=CC(=C1)Cl)NN=C(C#N)C#N
- InChIKey
- UGTJLJZQQFGTJD-UHFFFAOYSA-N
- XLogP
- 3.4
- Polar surface area
- 72 Ų
- H-bond donors
- 1
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
3,849 papers- CCCP-induced mitochondrial dysfunction - characterization and analysis of integrated stress response to cellular signaling and homeostasis.The FEBS journal · 2021
- CCCP induces hepatic stellate cell activation and liver fibrogenesis via mitochondrial and lysosomal dysfunction.Free radical biology & medicine · 2024
- Current mechanistic insights into the CCCP-induced cell survival response.Biochemical pharmacology · 2018
- CCCP Facilitates Aminoglycoside to Kill Late Stationary-Phase Escherichia coli by Elevating Hydroxyl Radical.ACS infectious diseases · 2023
- CCCP inhibits DPV infection in DEF cells by attenuating DPV manipulated ROS, apoptosis, and mitochondrial stability.Poultry science · 2024
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 204.02
Show 3 more facts
- chemical formula
- C₉H₅ClN₄
- canonical SMILES
- C1=CC(=CC(=C1)Cl)NN=C(C#N)C#N
- Commons category
- Carbonyl cyanide m-chlorophenyl hydrazone
Sources (2)
via Wikidata · CC0
Article · Italiano
Carbonil cianuro m-clorofenil idrazone (CCCF), è un composto chimico della classe degli ionofori che contiene nella struttura un gruppi nitrile e idrazone; svolge una funzione di inibitore chimico della fosforilazione ossidativa.È un acido debole lipido-solubile ed agisce da disgiungente mitocondriale. Generalmente CCCF causa la graduale distruzione delle cellule viventi e la morte dell'intero organismo.
Abstract from DBpedia / Wikipedia · CC BY-SA