Structure via PubChem · Public domain (PubChem)
chloroacetaldehyde
Sign in to saveAlso known as 2-Chloroacetaldehyde, 2-Chloroethanal, Chloroaldehyde, Monochloroacetaldehyde, 2-Chloro-1-ethanal
Chloroacetaldehyde is an organic compound with the formula ClCH2CHO. Like some related compounds, it is highly electrophilic reagent and a potentially dangerous alkylating agent. The compound is not normally encountered in the anhydrous form, but rather as the hemiacetal (ClCH2CH(OH))2O.
Chemical data
- Formula
- C2H3ClO
- Molecular weight
- 78.5 g/mol
- IUPAC name
- 2-chloroacetaldehyde
- SMILES
- C(C=O)Cl
- InChIKey
- QSKPIOLLBIHNAC-UHFFFAOYSA-N
- XLogP
- 0.3
- Polar surface area
- 17.1 Ų
- H-bond donors
- 0
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- aldehydes
- Mass
- 77.987
Show 11 more facts
- ionization energy
- 10.61
- immediately dangerous to life or health
- 144.45
- canonical SMILES
- C(C=O)Cl
- chemical formula
- C₂H₃ClO
- NIOSH Pocket Guide ID
- 0118
- density
- 1.19
- boiling point
- 85.5
- vapor pressure
- 100
- ceiling exposure limit
- 3
- Commons category
- Chloroacetaldehyde
- melting point
- -16.3
via Wikidata · CC0
~3 min read
Encyclopedic overview
6 sectionsContents
- Synthesis and occurrence
- Reactions
- Environmental aspects
- Safety
- See also
- References
Chloroacetaldehyde is an organic compound with the formula ClCH2CHO. Like some related compounds, it is highly electrophilic reagent and a potentially dangerous alkylating agent. The compound is not normally encountered in the anhydrous form, but rather as the hemiacetal (ClCH2CH(OH))2O.
Chloroacetaldehyde is a metabolite of the antineoplastic ifosfamide and believed to be responsible for some of the toxicity observed with ifosfamide.
Excerpted from Wikipedia’s “chloroacetaldehyde” article, available under the CC BY-SA 4.0 licence.