chlorozotocin

Chlorozotocin is a nitrosourea. It is used for cancer therapy.

In the Vinony graph

Within Vinony's link graph, chlorozotocin is referenced by 5 other articles, and connects out to medication, International Standard Book Number and chemical formula.

It sits within the topics Alkylating antineoplastic agents, Chemical pages without DrugBank identifier and Chloroethyl compounds.

Its subject is documented across 6 Wikipedia language editions.

Chemical data

Formula: C9H16ClN3O7
Molecular weight: 313.69 g/mol
IUPAC name: 1-(2-chloroethyl)-1-nitroso-3-[(2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl]urea
SMILES: C(CCl)N(C(=O)N[C@@H](C=O)[C@H]([C@@H]([C@@H](CO)O)O)O)N=O
InChIKey: MKQWTWSXVILIKJ-LXGUWJNJSA-N
XLogP: -2.6
Polar surface area: 160 Å²
H-bond donors: 5
H-bond acceptors: 8
Formal charge: 0

via PubChem

Research

206 papers

Chlorozotocin.IARC monographs on the evaluation of carcinogenic risks to humans · 1990
Chlorozotocin. Mechanism of reduced bone marrow toxicity in mice.The Journal of clinical investigation · 1979
Chlorozotocin.Report on carcinogens : carcinogen profiles · 2002
Chlorozotocin.Report on carcinogens : carcinogen profiles · 2004
L-Chlorozotocin.Journal of medicinal chemistry · 1979

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 313.067678

Show 5 more facts

chemical formula: C₉H₁₆ClN₃O₇
isomeric SMILES: C(CCl)N(C(=O)N[C@@H](C=O)[C@H]([C@@H]([C@@H](CO)O)O)O)N=O
canonical SMILES: C(CCl)N(C(=O)NC(C=O)C(C(C(CO)O)O)O)N=O
subject has role: carcinogen
Commons category: Chlorozotocin

Sources (3)

via Wikidata · CC0

~1 min read

Encyclopedic overview

1 sections

Contents

References

{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 293076130 | IUPAC_name = 2-{[(2-Chloroethyl)(nitroso)carbamoyl]amino}-2-deoxy-D-glucose | image = Chlorozotocin (Haworth).svg | image_class = skin-invert-image | width = 160 | alt = Haworth projection of chlorozotocin

Excerpted from Wikipedia’s “chlorozotocin” article, available under the CC BY-SA 4.0 licence.