Structure via PubChem · Public domain (PubChem)
chlorozotocin
Sign in to saveChlorozotocin is a nitrosourea. It is used for cancer therapy.
Chemical data
- Formula
- C9H16ClN3O7
- Molecular weight
- 313.69 g/mol
- IUPAC name
- 1-(2-chloroethyl)-1-nitroso-3-[(2R,3R,4S,5R)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl]urea
- SMILES
- C(CCl)N(C(=O)N[C@@H](C=O)[C@H]([C@@H]([C@@H](CO)O)O)O)N=O
- InChIKey
- MKQWTWSXVILIKJ-LXGUWJNJSA-N
- XLogP
- -2.6
- Polar surface area
- 160 Ų
- H-bond donors
- 5
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Research
206 papers- Chlorozotocin.IARC monographs on the evaluation of carcinogenic risks to humans · 1990
- Chlorozotocin. Mechanism of reduced bone marrow toxicity in mice.The Journal of clinical investigation · 1979
- Chlorozotocin.Report on carcinogens : carcinogen profiles · 2002
- Chlorozotocin.Report on carcinogens : carcinogen profiles · 2004
- L-Chlorozotocin.Journal of medicinal chemistry · 1979
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 313.067678
Show 5 more facts
- chemical formula
- C₉H₁₆ClN₃O₇
- isomeric SMILES
- C(CCl)N(C(=O)N[C@@H](C=O)[C@H]([C@@H]([C@@H](CO)O)O)O)N=O
- canonical SMILES
- C(CCl)N(C(=O)NC(C=O)C(C(C(CO)O)O)O)N=O
- subject has role
- carcinogen
- Commons category
- Chlorozotocin
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 293076130 | IUPAC_name = 2-{[(2-Chloroethyl)(nitroso)carbamoyl]amino}-2-deoxy-D-glucose | image = Chlorozotocin (Haworth).svg | image_class = skin-invert-image | width = 160 | alt = Haworth projection of chlorozotocin
| tradename = | pregnancy_AU = | pregnancy_US = | legal_AU = | legal_CA = | legal_UK = | legal_US =
Excerpted from Wikipedia’s “chlorozotocin” article, available under the CC BY-SA 4.0 licence.