CLDN17
Sign in to saveAlso known as claudin 17
Claudin-17 is a protein that in humans is encoded by the CLDN17 gene. It belongs to the group of claudins; claudins are cell-cell junction proteins that keep that maintains cell- and tissue-barrier function. It forms anion-selective paracellular channels and is localized mainly in kidney proximal tubules.
Gene data
CLDN17- Name
- claudin 17
- Type
- protein-coding
- Position
- 30,165,565–30,166,805 (−)
- Ensembl
- ENSG00000156282
- RefSeq RNA
- NM_012131.3
- RefSeq protein
- NP_036263.1
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is intronless and is clustered with CLDN8 on chromosome 21q22.11. [provided by RefSeq, Jun 2010].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
claudin 17
- Symbol
- CLDN17
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 21:30,165,565-30,166,805
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 7 more facts
- HomoloGene ID
- 8116
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/26285
- genomic end
- 30166805
- genomic start
- 30165565
- chromosome
- human chromosome 21
- cytogenetic location
- 21q21.3
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Claudin-17 is a protein that in humans is encoded by the CLDN17 gene. It belongs to the group of claudins; claudins are cell-cell junction proteins that keep that maintains cell- and tissue-barrier function. It forms anion-selective paracellular channels and is localized mainly in kidney proximal tubules.
==References==
Excerpted from Wikipedia’s “CLDN17” article, available under the CC BY-SA 4.0 licence.