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clofexamide

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EntityQ5134877· pop 5· linked from 4 articles

clofexamide

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Clofexamide (or amichlophene) is an antidepressant that was a component of the drug combination clofezone, the other being the nonsteroidal anti-inflammatory drug (NSAID) phenylbutazone. Clofezone was used to treat joint and muscular pain, but is not marketed any more.

Chemical data

Formula
C14H21ClN2O2
Molecular weight
284.78 g/mol
IUPAC name
2-(4-chlorophenoxy)-N-[2-(diethylamino)ethyl]acetamide
SMILES
CCN(CC)CCNC(=O)COC1=CC=C(C=C1)Cl
InChIKey
UORGKWWJEQDTGX-UHFFFAOYSA-N
XLogP
2.6
Polar surface area
41.6 Ų
H-bond donors
1
H-bond acceptors
3
Formal charge
0

via PubChem

Drug data · ChEMBL

Max clinical phase
Phase 2
Molecule type
Small molecule

via ChEMBL · EBI

Wikidata facts

Mass
284.129
Show 2 more facts
chemical formula
C₁₄H₂₁ClN₂O₂
canonical SMILES
CCN(CC)CCNC(=O)COC1=CC=C(C=C1)Cl
Sources (2)

via Wikidata · CC0

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Encyclopedic overview

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Contents
  • References

Clofexamide (or amichlophene) is an antidepressant that was a component of the drug combination clofezone, the other being the nonsteroidal anti-inflammatory drug (NSAID) phenylbutazone. Clofezone was used to treat joint and muscular pain, but is not marketed any more.

== References ==

Excerpted from Wikipedia’s “clofexamide” article, available under the CC BY-SA 4.0 licence.

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