Cobicistat, sold under the brand name Tybost, is a medication for use in the treatment of human immunodeficiency virus infection (HIV/AIDS). Its major mechanism of action is through the inhibition of human CYP3A proteins.
via PubMed
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 451564721 | IUPAC_name = 1,3-thiazol-5-ylmethyl [(2R,5R)-5-{[(2S)-2-[(methyl{[2-(propan-2-yl)-1,3-thiazol-4-yl]methyl}carbamoyl)amino]-4-(morpholin-4-yl)butanoyl]amino}-1,6-diphenylhexan-2-yl]carbamate | image = Cobicistat structure.svg | image_class = skin-invert-image | width = 275 | drug_name =
| pronounce = | tradename = Tybost | Drugs.com = | MedlinePlus = a616029 | licence_EU = yes | licence_US = | DailyMedID = Cobicistat | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = Rx-only | legal_status = | dependency_liability = | routes_of_administration = | ATC_prefix = V03 | ATC_suffix = AX03 | ATC_supplemental =
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).