COG1

Also known as CDG2G, LDLB, component of oligomeric golgi complex 1

Conserved oligomeric Golgi complex subunit 1 is a protein that in humans is encoded by the COG1 gene.

Gene data

COG1

Name: component of oligomeric golgi complex 1
Type: protein-coding
Position: 73,193,029–73,218,530 (+)
Aliases: CDG2G, LDLB
Ensembl: ENSG00000166685
RefSeq RNA: NM_018714.3
RefSeq protein: NP_061184.1

The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that this protein is required for steps in the normal medial and trans Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex. [provided by RefSeq, Jul 2008].

Gene Ontology

Biological process

retrograde transport, vesicle recycling within Golgi intra-Golgi vesicle-mediated transport intra-Golgi vesicle-mediated transport Golgi organization Golgi organization

Molecular function

protein binding

Cellular component

Golgi membrane Golgi membrane Golgi membrane Golgi apparatus Golgi apparatus COG complex COG complex COG complex

Pathways

Disease ER to Golgi Anterograde Transport Membrane Trafficking Metabolism of proteins Asparagine N-linked glycosylation Vesicle-mediated transport Infectious disease Post-translational protein modification COPI-mediated anterograde transport Intra-Golgi traffic

via MyGene.info

Gene · Ensembl

component of oligomeric golgi complex 1

Symbol: COG1
Biotype: Protein coding
Organism: Homo sapiens
Location: 17:73,193,029-73,218,530
Strand: Forward (+)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 8411
genomic start: 73193055
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/9382
genomic end: 71204646
chromosome: human chromosome 17
cytogenetic location: 17q25.1

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Encyclopedic overview

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Conserved oligomeric Golgi complex subunit 1 is a protein that in humans is encoded by the COG1 gene.

The protein encoded by this gene is one of eight proteins (Cog1-8) which form a Golgi-localized complex (COG) required for normal Golgi morphology and function. It is thought that this protein is required for steps in the normal medial and trans-Golgi-associated processing of glycoconjugates and plays a role in the organization of the Golgi-localized complex.

Excerpted from Wikipedia’s “COG1” article, available under the CC BY-SA 4.0 licence.