COG4
Sign in to saveAlso known as CDG2J, COD1, component of oligomeric golgi complex 4, SWILS
Conserved oligomeric Golgi complex subunit 4 is a protein that in humans is encoded by the COG4 gene.
Gene data
COG4- Name
- component of oligomeric golgi complex 4
- Type
- protein-coding
- Aliases
- CDG2J, COD1, SWILS
The protein encoded by this gene is a component of an oligomeric protein complex involved in the structure and function of the Golgi apparatus. Defects in this gene may be a cause of congenital disorder of glycosylation type IIj. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010].
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 7155
- exact match
- identifiers.org/ncbigene/25839
- genomic end
- 70523560
- genomic start
- 70514471
- cytogenetic location
- 16q22.1
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Conserved oligomeric Golgi complex subunit 4 is a protein that in humans is encoded by the COG4 gene.
Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG4 (Ungar et al., 2002).[supplied by OMIM]