Skip to content
Vinony
English
EnglishDeutschEspañolFrançaisNederlandsPortuguêsSvenskaالعربية
GeneQ18037734· pop 5· linked from 9 articles

COG4

Sign in to save

Also known as CDG2J, COD1, component of oligomeric golgi complex 4, SWILS

Conserved oligomeric Golgi complex subunit 4 is a protein that in humans is encoded by the COG4 gene.

Gene data

COG4
Name
component of oligomeric golgi complex 4
Type
protein-coding
Position
70,480,567–70,523,582 (−)
Aliases
CDG2J, COD1, SWILS
Ensembl
ENSG00000103051
RefSeq RNA
NM_001195139.2, NM_001365426.1, NM_015386.3, NM_145818.1, NR_158212.1
RefSeq protein
NP_001182068.2, NP_001352355.1, NP_056201.2

The protein encoded by this gene is a component of an oligomeric protein complex involved in the structure and function of the Golgi apparatus. Defects in this gene may be a cause of congenital disorder of glycosylation type IIj. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2010].

Gene Ontology

Pathways

ER to Golgi Anterograde TransportMembrane TraffickingMetabolism of proteinsAsparagine N-linked glycosylationVesicle-mediated transportPost-translational protein modificationCOPI-mediated anterograde transportIntra-Golgi trafficRetrograde transport at the Trans-Golgi-NetworkIntra-Golgi and retrograde Golgi-to-ER traffic

via MyGene.info

Gene · Ensembl

component of oligomeric golgi complex 4

Symbol
COG4
Biotype
Protein coding
Organism
Homo sapiens
Location
16:70,480,567-70,523,582
Strand
Reverse (−)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of
gene
Show 7 more facts
HomoloGene ID
7155
found in taxon
Homo sapiens
exact match
identifiers.org/ncbigene/25839
genomic end
70523560
genomic start
70514471
chromosome
human chromosome 16
cytogenetic location
16q22.1
Sources (5)

via Wikidata · CC0

~1 min read

Encyclopedic overview

5 sections
Contents
  • Interactions
  • Clinical
  • References
  • Further reading
  • External links

Conserved oligomeric Golgi complex subunit 4 is a protein that in humans is encoded by the COG4 gene.

Multiprotein complexes are key determinants of Golgi apparatus structure and its capacity for intracellular transport and glycoprotein modification. Several complexes have been identified, including the Golgi transport complex (GTC), the LDLC complex, which is involved in glycosylation reactions, and the SEC34 complex, which is involved in vesicular transport. These 3 complexes are identical and have been termed the conserved oligomeric Golgi (COG) complex, which includes COG4 (Ungar et al., 2002).[supplied by OMIM]

Excerpted from Wikipedia’s “COG4” article, available under the CC BY-SA 4.0 licence.

Available in 5 languages

via Wikidata sitelinks · CC0