CPhos is a phosphine ligand derived from biphenyl. It is a white solid that is soluble in organic solvents.
CPhos is a phosphine ligand derived from biphenyl. It is a white solid that is soluble in organic solvents.
Its palladium complexes exhibit high activity for Negishi coupling reactions involving aryl bromides, chlorides and triflates. CPhos mediated reactions performed with secondary (sp3) alkylzinc halides often give excellent yields, with low conversion to the frequently encountered primary substituted by-products.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).