CPhos
Sign in to saveCPhos is a phosphine ligand derived from biphenyl. It is a white solid that is soluble in organic solvents.
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 436.3007359420001
Show 2 more facts
- canonical SMILES
- CN(C)C1=C(C(=CC=C1)N(C)C)C2=CC=CC=C2P(C3CCCCC3)C4CCCCC4
- chemical formula
- C₂₈H₄₁N₂P
Sources (2)
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Encyclopedic overview
4 sectionsContents
- Utility in Negishi Coupling
- See also
- References
- External links
CPhos is a phosphine ligand derived from biphenyl. It is a white solid that is soluble in organic solvents.
Its palladium complexes exhibit high activity for Negishi coupling reactions involving aryl bromides, chlorides and triflates. CPhos mediated reactions performed with secondary (sp3) alkylzinc halides often give excellent yields, with low conversion to the frequently encountered primary substituted by-products.
Excerpted from Wikipedia’s “CPhos” article, available under the CC BY-SA 4.0 licence.