CRABP1
Sign in to saveAlso known as CRABP, CRABP-I, CRABPI, RBP5, cellular retinoic acid binding protein 1
Cellular retinoic acid-binding protein 1 is a protein that in humans is encoded by the CRABP1 gene.
Gene data
CRABP1- Name
- cellular retinoic acid binding protein 1
- Type
- protein-coding
- Position
- 78,340,260–78,348,250 (+)
- Aliases
- CRABP, CRABP-I, CRABPI, RBP5
- Ensembl
- ENSG00000166426
- RefSeq RNA
- NM_004378.3
- RefSeq protein
- NP_004369.1
This gene encodes a specific binding protein for a vitamin A family member and is thought to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid at specific sites within the nucleus, which may contribute to vitamin A-directed differentiation in epithelial tissue. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
cellular retinoic acid binding protein 1
- Symbol
- CRABP1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 15:78,340,260-78,348,250
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein CRABP1 PDB 1cbi.png
Show 9 more facts
- exact match
- identifiers.org/ncbigene/1381
- HomoloGene ID
- 3222
- found in taxon
- Homo sapiens
- genomic start
- 78340353
- chromosome
- human chromosome 15
- genomic end
- 78348225
- cytogenetic location
- 15q25.1
- expressed in
- trigeminal ganglion
- Commons category
- CRABP1
Sources (3)
via Wikidata · CC0
~3 min read
Encyclopedic overview
4 sectionsContents
- Function
- References
- Further reading
- External links
Cellular retinoic acid-binding protein 1 is a protein that in humans is encoded by the CRABP1 gene.
CRABP1 is assumed to play an important role in retinoic acid-mediated differentiation and proliferation processes. It is structurally similar to the cellular retinol-binding proteins, but binds only retinoic acid. CRABP1 is constitutively expressed and is believed to have different functions in the cell than the related CRABP2.
Excerpted from Wikipedia’s “CRABP1” article, available under the CC BY-SA 4.0 licence.