CST11
Sign in to saveAlso known as CST8L, CTES2, SC13, dJ322G13.6, cystatin 11
Cystatin-11 is a protein that in humans is encoded by the CST11 gene.
Gene data
CST11- Name
- cystatin 11
- Type
- protein-coding
- Position
- 23,450,403–23,453,210 (−)
- Aliases
- CST8L, CTES2, SC13, dJ322G13.6
- Ensembl
- ENSG00000125831
- RefSeq RNA
- NM_080830.3, NM_130794.2
- RefSeq protein
- NP_543020.2, NP_570612.1
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes an epididymal-specific protein shown to have antimicrobial activity against E. coli. Alternative splicing yields two variants encoding distinct isoforms. [provided by RefSeq, Sep 2014].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
cystatin 11
- Symbol
- CST11
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:23,450,403-23,453,210
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 15634
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/140880
- genomic end
- 23452876
- genomic start
- 23431040
- chromosome
- human chromosome 20
- cytogenetic location
- 20p11.21
- expressed in
- fundus
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- References
- External links
- Further reading
Cystatin-11 is a protein that in humans is encoded by the CST11 gene.
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity.
Excerpted from Wikipedia’s “CST11” article, available under the CC BY-SA 4.0 licence.