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Sign in to saveCyclopia (named after the Greek mythology characters cyclopes), also known as alobar holoprosencephaly, is the most extreme form of holoprosencephaly and is a congenital disorder (birth defect) characterized by the failure of the embryonic prosencephalon to properly divide the orbits of the eye into two cavities. Its incidence is 1 in 16,000 in born animals and 1 in 200 in miscarried fetuses.
Key facts
- Medical condition (new).name
- Cyclopia
- Medical condition (new).synonyms
- Cyclocephaly, synophthalmia, monophthalmia
- Medical condition (new).image
- Cyclopia fetuses.jpg
- Medical condition (new).caption
- Fetuses with cyclopia
- Medical condition (new).field
- Medical genetics
- Medical condition (new).onset
- During embryonic development
- Medical condition (new).duration
- Lifelong
- Medical condition (new).prognosis
- Invariably fatal
- Medical condition (new).frequency
- 1 in 100,000 births
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- Cyclopia (medicine)
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Article
10 sectionsContents
- Signs and symptoms
- Causes
- Notable cases
- Cultural significance
- Gallery
- Humans
- Animals
- See also
- References
- External links
Cyclopia (named after the Greek mythology characters cyclopes), also known as alobar holoprosencephaly, is the most extreme form of holoprosencephaly and is a congenital disorder (birth defect) characterized by the failure of the embryonic prosencephalon to properly divide the orbits of the eye into two cavities. Its incidence is 1 in 16,000 in born animals and 1 in 200 in miscarried fetuses.
== Signs and symptoms == Typically, the nose is either missing or not functional. This deformity (called proboscis) forms above the center eye and is characteristic of a form of cyclopia called rhinencephaly or rhinocephaly. Most such embryos are either naturally miscarried or stillborn upon delivery.