DEDD

Name

death effector domain containing

Type

protein-coding

Position

161,120,957–161,133,280 (−)

Aliases

CASP8IP1, DEDD1, DEDPro1, DEFT, FLDED-1, FLDED1, KE05

Ensembl

ENSG00000158796

RefSeq RNA

NM_001039711.2, NM_001039712.2, NM_001330765.2, NM_004216.2, NM_032998.3

RefSeq protein

NP_001034800.1, NP_001034801.1, NP_001317694.1, NP_127491.1, XP_005245656.1

This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

death effector domain containing

Symbol

DEDD

Biotype

Protein coding

Organism

Homo sapiens

Location

1:161,120,957-161,133,280

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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