DERL3
Sign in to saveAlso known as C22orf14, IZP6, LLN2, derlin-3, derlin 3
Derlin-3 is a protein that in humans is encoded by the DERL3 gene.
Gene data
DERL3- Name
- derlin 3
- Type
- protein-coding
- Position
- 23,834,503–23,839,131 (−)
- Aliases
- C22orf14, IZP6, LLN2, derlin-3
- Ensembl
- ENSG00000099958
- RefSeq RNA
- NM_001002862.3, NM_001135751.2, NM_001363072.2, NM_198440.4, XM_011530505.4
- RefSeq protein
- NP_001002862.1, NP_001129223.1, NP_001350001.1, NP_940842.2, XP_011528807.1
The protein encoded by this gene belongs to the derlin family, and resides in the endoplasmic reticulum (ER). Proteins that are unfolded or misfolded in the ER must be refolded or degraded to maintain the homeostasis of the ER. This protein appears to be involved in the degradation of misfolded glycoproteins in the ER. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Oct 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
derlin 3
- Symbol
- DERL3
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- Chr HSCHR22_1_CTG7:70,865-75,490
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 41566
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/91319
- chromosome
- human chromosome 22
- genomic start
- 24176690
- genomic end
- 24181315
- cytogenetic location
- 22q11.23
- expressed in
- rectum
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- Further reading
Derlin-3 is a protein that in humans is encoded by the DERL3 gene.
== See also == Derlin-1 Derlin-2
Excerpted from Wikipedia’s “DERL3” article, available under the CC BY-SA 4.0 licence.