Structure via PubChem · Public domain (PubChem)
dichloroacetic acid
Sign in to saveAlso known as DCA, dichloracetic acid, dichloroacetate, 2,2-dichloroacetic acid, bichloracetic acid
chemical compound
Chemical data
- Formula
- C2H2Cl2O2
- Molecular weight
- 128.94 g/mol
- IUPAC name
- 2,2-dichloroacetic acid
- SMILES
- C(C(=O)O)(Cl)Cl
- InChIKey
- JXTHNDFMNIQAHM-UHFFFAOYSA-N
- XLogP
- 0.9
- Polar surface area
- 37.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
- Indications
- glioblastoma multiforme, neoplasm, head and neck malignant neoplasia, Hyperglycemia
via ChEMBL · EBI
Research
1,784 papers- Dichloroacetic acid.IARC monographs on the evaluation of carcinogenic risks to humans · 1995
- Cytotoxic derivatives of dichloroacetic acid and some metal complexes.Archiv der Pharmazie · 2022
- Dichloroacetic acid and rapamycin synergistically inhibit tumor progression.Journal of Zhejiang University. Science. B · 2023
- Dichloroacetic acid and trichloroacetic acid as disinfection by-products in drinking water are endocrine-disrupting chemicals.Journal of hazardous materials · 2024
- Dichloroacetic Acid Enhances Photodynamic Therapy-Induced Regulated Cell Death in PANC-1 Pancreatic Cancer Cell Line.International journal of molecular sciences · 2025
via PubMed
Wikidata facts
- Has part
- chlorine
- Mass
- 127.943
Show 7 more facts
- chemical formula
- C₂H₂Cl₂O₂
- canonical SMILES
- C(C(=O)O)(Cl)Cl
- Commons category
- Dichloroacetic acid
- pKa
- 1.30
- melting point
- 13.5
- found in taxon
- Asparagopsis taxiformis
- subject has role
- carcinogen
via Wikidata · CC0
~10 min read
Encyclopedic overview
Names
Preferred IUPAC name Dichloroacetic acid
Excerpted from Wikipedia’s “dichloroacetic acid” article, available under the CC BY-SA 4.0 licence.