Structure via PubChem · Public domain (PubChem)
dihydrouridine
Sign in to saveAlso known as 1-beta-D-ribofuranosylhydrouracil, 3,4-Dihydrouridine, d, Dihydro-1-beta-delta-ribofuranosyl-2,4(1H,3H)-Pyrimidinedione, Dihydro-1-b-D-ribofuranosyl-2,4(1H,3H)-Pyrimidinedione, 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione
Dihydrouridine (abbreviated as D, hU, DHU, or UH2) is a pyrimidine nucleoside which is the result of adding two hydrogen atoms to a uridine, making it a fully saturated pyrimidine ring with no remaining double bonds. D is found in tRNA and rRNA molecules as a nucleoside; the corresponding nucleobase is 5,6-dihydrouracil.
Chemical data
- Formula
- C9H14N2O6
- Molecular weight
- 246.22 g/mol
- IUPAC name
- 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3-diazinane-2,4-dione
- SMILES
- C1CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
- InChIKey
- ZPTBLXKRQACLCR-XVFCMESISA-N
- XLogP
- -2.1
- Polar surface area
- 119 Ų
- H-bond donors
- 4
- H-bond acceptors
- 6
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Has part
- carbon
- Mass
- 246.085186
Show 4 more facts
- chemical formula
- C₉H₁₄N₂O₆
- canonical SMILES
- C1CN(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
- isomeric SMILES
- C1CN(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
- Commons category
- Dihydrouridine
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
1 sectionsContents
- References
Dihydrouridine (abbreviated as D, hU, DHU, or UH2) is a pyrimidine nucleoside which is the result of adding two hydrogen atoms to a uridine, making it a fully saturated pyrimidine ring with no remaining double bonds. D is found in tRNA and rRNA molecules as a nucleoside; the corresponding nucleobase is 5,6-dihydrouracil.
thumb|none|Structure of base pair Adenine Dihydrouracil (AD)
Excerpted from Wikipedia’s “dihydrouridine” article, available under the CC BY-SA 4.0 licence.