2,6-diaminopurine
Also known as 9H-purine-2,6-diamine, Z, 2-aminoadenine, diaminopurine, aminoadenine
2,6-diaminopurine (2,6-DAP, also known as 2-aminoadenine, standard IUPAC symbol n2A) is a compound once used in the treatment of leukemia. It is found instead of adenine (A) in the genetic material of some bacteriophage viruses,
Research
635 papers- 2,6-diaminopurine (Z)-containing toehold probes improve genotyping sensitivity.Biotechnology and bioengineering · 2024
- Transcriptional Perturbations of 2,6-Diaminopurine and 2-Aminopurine.ACS chemical biology · 2022
- 2,6-diaminopurine promotes repair of DNA lesions under prebiotic conditions.Nature communications · 2021
- Electronic relaxation mechanism of 9-methyl-2,6-diaminopurine and 2,6-diaminopurine-2'-deoxyribose in solution.Photochemistry and photobiology · 2024
- 2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations.Nature communications · 2020
via PubMed
Article
6 sectionsContents
- Abbreviations
- In viruses
- Biosynthesis
- In cellular life
- Bioengineering
- References
2,6-diaminopurine (2,6-DAP, also known as 2-aminoadenine, standard IUPAC symbol n2A) is a compound once used in the treatment of leukemia. It is found instead of adenine (A) in the genetic material of some bacteriophage viruses,
In August 2011, a report, based on NASA studies with meteorites found on Earth, was published suggesting 2,6-diaminopurine and related organic molecules, including the DNA and RNA components adenine and guanine, may have been formed extraterrestrially in outer space.