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EntityQ2522· pop 43· linked from 719 articles

dioxins and dioxin-like compounds

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Also known as PCDD/F & PCB, Dioxin-like compounds, dioxins, Dioxin

class of chemical compounds

~40 min read

Encyclopedic overview

Dioxins and dioxin-like compounds (DLCs) are a group of chemical compounds that are persistent organic pollutants (POPs) in the environment. They are mostly by-products of burning or various industrial processes or, in the case of dioxin-like PCBs and PBBs, unwanted minor components of intentionally produced mixtures.

Some of them are highly toxic, but the toxicity among them varies 30,000-fold. They are grouped together because their mechanism of action is the same. They activate the aryl hydrocarbon receptor (AH receptor), albeit with very different binding affinities, leading to high differences in toxicity and other effects. They include:

Excerpted from Wikipedia’s “dioxins and dioxin-like compounds” article, available under the CC BY-SA 4.0 licence.